Ryan Braun, a famous American baseball player, tested positive for anabolic steroids. This circumstance caused unusual debates. This baseball player will be probably suspended. His analytical positives have caused extremely hot debates.
Braun had an essentially increased T\E ratio in a urine sample. This American baseball player was tested in October, 2011. According to certain sources, his T\E ratio had the most increased indexes that had ever been shown by T\E ratio tests. The T\E ratio showed that his level was twice of the most enhanced level which was ever determined by T\E ratio tests.
This led to reports of several sportswriters. They wrote that Ryan Braun had had very increased level of testosterone. However the urinary test showed increased indexes, the information of sportswriters is misleading.
It is necessary to understand that the T\E ratio is just a ratio. It doesn’t show serum level of testosterone in blood. It just testifies about testosterone of exogenous origin.
A laboratory in Montreal that was authorized by the WADA used isotope ratio testing in order to confirm the T\E ratio test. This test doesn’t display absolute testosterone level too. It determines just the origin of testosterone. As for Braun, it was determined that testosterone of his blood had possessed exogenous origin. It means that it wasn’t made inside of his organism but it was originated outside of his organism. Thus, the tests defined that this baseball player had administrated this hormone.
But a representative for the Braun camp noted that this baseball player wasn’t guilty. He noticed that this baseball player hadn’t had any intentions to break the rules of the WADA.
It is difficult to explain what happens in this situation. A spokesperson noticed that unusual things relate to this case.
There was a decision to test this person once again. Ryan Braun submitted. The second T\E ratio test displayed absolutely opposite indexes. It showed normal indexes. How is it possible to understand these things? The first T\E ratio test showed very enhanced testosterone levels, the second one showed normal levels. Could you imagine? There are a lot of explanations related to his positives.
What will say the baseball player for his defense? It is not clear. Everybody is waiting for his defense. This situation causes enhanced curiosity. Has Braun used testosterone?
Показаны сообщения с ярлыком new potential drugs. Показать все сообщения
Показаны сообщения с ярлыком new potential drugs. Показать все сообщения
пятница, 6 января 2012 г.
среда, 21 декабря 2011 г.
Potential alternative medicines to anabolic steroids
Specialists try to find alternative preparations to anabolic steroids and other performance-enhancing drugs. They claim that sportsmen may soon have another way to increase muscles. The Salk Institute has pointed out that the efforts of the specialists have got success. Late researches have shown that blocking of a genome regulator that is known as “NCoR1” leads to increase of muscle size, energy and endurance. The leader of the researches conducted in the Salk Institute, Ronald Evans, notices that this knowledge can lead to elaboration of certain new preparations which will benefit not only for athletes and bodybuilders who train but also for persons that are sedentary.
The scientists of the Salk Institute notice about people who are not able to perform physical exercises because they have different health problems, such as diabetes, frailty, immobility and other physical or mental factors that lead to sedentary lifestyle. The scientists try to elaborate certain specific drugs which could benefit for sedentary persons so, as exercises benefit for healthy people. Now they experiment with sedentary mice.
As for anabolic steroids, they can lead to increase of muscle size in sedentary individuals. But individuals that take anabolic steroids must train and alter their diets in order to achieve more essential effects.
If new medicines that suppress NCoR1 are elaborated by scientists successfully, they will lead to significant changes in sedentary people. But can you imagine which benefits will be caused in sportsmen?
But there is also an important difference between anabolic steroids and NCoR1 suppression. It is known that anabolic steroids cause unwanted symptoms; some of them can be quite dangerous for health and even life-threatening. Moreover, anabolic steroids can cause severe unwanted results especially in females. But as for NCoR1 suppression, scientists are sure that medications which will suppress this genome regulator will not lead to undesirable effects.
There is an article about NCoR1 suppression that has the following title: “NCoR1 Is a Conserved Physiological Modulator of Muscle Mass and Oxidative Function”. It represents results of various experiments that enrolled mice and nematodes. The experiments have displayed that NCoR1 suppression benefits for muscle mass significantly. The mice with suppression of this genome regulator had got more enhanced muscles and ran faster than others.
Unfortunately, the mice with NCoR1 suppression were not compared with the mice which received anabolic steroids. If these two types of mice were compared, the results of the experiments would be very precious for further researches and conclusions.
It is possible to mention that elder people and individuals that suffer of muscle dystrophy will be soon enrolled in studies to check benefits of new potential drugs.
The scientists of the Salk Institute notice about people who are not able to perform physical exercises because they have different health problems, such as diabetes, frailty, immobility and other physical or mental factors that lead to sedentary lifestyle. The scientists try to elaborate certain specific drugs which could benefit for sedentary persons so, as exercises benefit for healthy people. Now they experiment with sedentary mice.
As for anabolic steroids, they can lead to increase of muscle size in sedentary individuals. But individuals that take anabolic steroids must train and alter their diets in order to achieve more essential effects.
If new medicines that suppress NCoR1 are elaborated by scientists successfully, they will lead to significant changes in sedentary people. But can you imagine which benefits will be caused in sportsmen?
But there is also an important difference between anabolic steroids and NCoR1 suppression. It is known that anabolic steroids cause unwanted symptoms; some of them can be quite dangerous for health and even life-threatening. Moreover, anabolic steroids can cause severe unwanted results especially in females. But as for NCoR1 suppression, scientists are sure that medications which will suppress this genome regulator will not lead to undesirable effects.
There is an article about NCoR1 suppression that has the following title: “NCoR1 Is a Conserved Physiological Modulator of Muscle Mass and Oxidative Function”. It represents results of various experiments that enrolled mice and nematodes. The experiments have displayed that NCoR1 suppression benefits for muscle mass significantly. The mice with suppression of this genome regulator had got more enhanced muscles and ran faster than others.
Unfortunately, the mice with NCoR1 suppression were not compared with the mice which received anabolic steroids. If these two types of mice were compared, the results of the experiments would be very precious for further researches and conclusions.
It is possible to mention that elder people and individuals that suffer of muscle dystrophy will be soon enrolled in studies to check benefits of new potential drugs.
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