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среда, 21 декабря 2011 г.

Potential alternative medicines to anabolic steroids

Specialists try to find alternative preparations to anabolic steroids and other performance-enhancing drugs. They claim that sportsmen may soon have another way to increase muscles. The Salk Institute has pointed out that the efforts of the specialists have got success. Late researches have shown that blocking of a genome regulator that is known as “NCoR1” leads to increase of muscle size, energy and endurance. The leader of the researches conducted in the Salk Institute, Ronald Evans, notices that this knowledge can lead to elaboration of certain new preparations which will benefit not only for athletes and bodybuilders who train but also for persons that are sedentary.
The scientists of the Salk Institute notice about people who are not able to perform physical exercises because they have different health problems, such as diabetes, frailty, immobility and other physical or mental factors that lead to sedentary lifestyle. The scientists try to elaborate certain specific drugs which could benefit for sedentary persons so, as exercises benefit for healthy people. Now they experiment with sedentary mice.
As for anabolic steroids, they can lead to increase of muscle size in sedentary individuals. But individuals that take anabolic steroids must train and alter their diets in order to achieve more essential effects.
If new medicines that suppress NCoR1 are elaborated by scientists successfully, they will lead to significant changes in sedentary people. But can you imagine which benefits will be caused in sportsmen?
But there is also an important difference between anabolic steroids and NCoR1 suppression. It is known that anabolic steroids cause unwanted symptoms; some of them can be quite dangerous for health and even life-threatening. Moreover, anabolic steroids can cause severe unwanted results especially in females. But as for NCoR1 suppression, scientists are sure that medications which will suppress this genome regulator will not lead to undesirable effects.
There is an article about NCoR1 suppression that has the following title: “NCoR1 Is a Conserved Physiological Modulator of Muscle Mass and Oxidative Function”. It represents results of various experiments that enrolled mice and nematodes. The experiments have displayed that NCoR1 suppression benefits for muscle mass significantly. The mice with suppression of this genome regulator had got more enhanced muscles and ran faster than others.
Unfortunately, the mice with NCoR1 suppression were not compared with the mice which received anabolic steroids. If these two types of mice were compared, the results of the experiments would be very precious for further researches and conclusions.
It is possible to mention that elder people and individuals that suffer of muscle dystrophy will be soon enrolled in studies to check benefits of new potential drugs.

понедельник, 12 декабря 2011 г.

Why doesn’t Laraque identify names of steroid users in his book?

Georges Laraque wrote his autobiography in a book “The story of the NHL’s unlikeliest tough guy”. He desired to tell about his biography to others. Georges Laraque noticed also about intake of anabolic steroids in the National Hockey League (NHL). These aspects about steroids use in NHL seemed to be very interesting. The Canadian press published only the quotes connected with this eternal subject. The rest of the book was neglected.
Georges Laraque pointed out in an interview that he had never taken performance-enhancing drugs. Furthermore, the author noted that he hadn’t mentioned any names of the sportsmen that had administrated steroids. The book is indeed an autobiography.
The author mentions about certain ways to determine whether a hockey player utilizes steroids and other performance-enhancing drugs or not. Here are 2 ways noticed by him:
1. A hockey player whose weight has been increased by more than 40 pounds in a short period of time must be taking performance-enhancing drugs.
2. A hockey player that reduces his weight significantly in short period of time in order to correspond to the rules of the Winter Olympics must be administrating steroids.

Undoubtedly, all sportsmen, including hockey players, know that they will be tested for steroids and other performance-enhancing drugs by the WADA. That’s why they stop taking the forbidden medications certain time before the Olympics. It helps them to avoid risk of testing positive for these medicines.
But this is not the chief idea of the book. The author desired to display that a child is required to put incredible efforts to become a good professional sportsperson in spite of racial intolerance and bullying. But the media is not interested in this subject. The press intends to publish stories connected with intake of steroids by athletes.
It was not the goal of the author to name the hockey players that took steroids.
Of course, the media tries to convince George Laraque to name steroid users of the NHL.